Karver Laboratory (CSH-017)
Summary 🟡 ~
- Owner Unit: College of Science and Health
- Sub-unit: Chemistry and Biochemistry
- Content Type: center
- Campus/Location: Lincoln Park (McGowan South 321D office; 325 lab)
- Last Verified: May 30, 2026
Description & capabilities
Faculty medicinal and chemical-biology research group developing inhibitors and selective substrates for inflammatory caspases (caspase-1, -4, -5). Work combines synthetic organic chemistry, biochemical assays, fluorogenic peptide substrates, and structure–activity relationship (SAR) profiling.
Access status
- Level: yellow (
Negotiated Access) - Rationale: Karver Lab faculty profile documents McGowan South office and lab rooms; access through chemistry research affiliation.
- Access URL: www.depaul.edu/faculty/caitlin-e-karver
- Contact name: Caitlin E. Karver
- Contact email: ckarver@depaul.edu
- Verification date: 2026-05-30
- Source URLs:
- www.depaul.edu/faculty/caitlin-e-karver
Verification
- Status: likely (
~) - Confidence: 82/100
- Rationale: Faculty-profile-anchored Karver Lab with published office/lab rooms and research focus.
- Last verified: 2026-05-30
- Evidence:
- DePaul faculty profile McGowan South 321D/325 and caspase research program
Equipment
Find this resource from the Equipment catalog or site search (e.g. “3D printers”, “laser cutter”, “NMR”).
| Category | Specific equipment |
|---|---|
| Spectrometers | Fluorogenic peptide-substrate assays; FRET-based caspase activity monitoring |
| Lab sample processing | Small-molecule synthesis and biochemical caspase inhibitor screening (McGowan South 325) |
Source: Karver DePaul faculty profile (May 2026). Last verified: May 28, 2026.
Contacts (resource-level)
- Website: Caitlin E. Karver — DePaul faculty profile
- Email: Caitlin E. Karver
Last verified: May 30, 2026.
People & contacts
Named contacts from the people registry when publicly documented.
- Caitlin E. Karver (Faculty lead) — ckarver@depaul.edu · Profile
- Carey Southern (Affiliated faculty) — CSOUTHE2@depaul.edu · Profile
- Kyle A. Grice (Affiliated faculty) — kgrice1@depaul.edu · Profile
Source URL
Official links and email are listed under Contacts above.
Documented Relationships
Medicinal chemistry research group; joint FRET-substrate projects with Southern Lab ([CSH-018](../CSH/CSH-018.md)) — documented in PUB-013, Design and Application of a Fluorogenic Assay for Monitoring Inflammatory Caspase Activity (DOI); uses shared McGowan instrumentation (CSH-001). Department chair also directs CSH-001/CSH-002/CSH-003 administration.
Linked Relationship IDs
- CSH-001 - Chemistry Core Instrumentation & Machine Shop
- CSH-002 - Chemistry Teaching Laboratories
- CSH-003 - Environmental Science & Chemistry Building (McGowan)
- CSH-016 - Grice Laboratory
- CSH-018 - Southern Laboratory
Notes
Faculty-profile-anchored lab resource (May 2026).